【IL 13】重组人白介素-13 产品报价 ¥800/2μg ¥2080/10μg ¥74880/1mg 背景资料 IL13 is an immunoregulatory cytokine produced primarily by activated Th2 cells. IL-13 is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4. 产品描述 人白介素-13重组蛋白是在大肠杆菌中重组表达的,是一条单链、非糖基化的多肽链,包含有112个氨基酸,分子量为12kDa。该人白介素-13重组蛋白较终由标准的色谱技术纯化出。 来源宿主 大肠杆菌中重组表达 序列 GPVPPSTALRELIEELVNITQNQKAPLCNGSMVWSINLTAGMYCAALESLINVS GCSAIEKTQRMLSGFCPHKVSAGQFSSLHVRDTKIEVAQFVKDLLLHLKKLFRE GRFN. 溶解建议 提供的人白介素-13(IL 13)产品为过滤灭菌的白色冻干粉末;该冻干粉末是从含1mg/ml人白介素-13(IL 13)的1X PBS(pH 7.2)溶液中冻干产生的。我们建议加无菌的18MΩ-cm水以配制工作储存液到100μg/ml,后继实验过程中可根据实验要求进一步稀释。 保存建议 人白介素-13(IL 13)在室温可保存3周,或置于-18℃冻存用于长期保存。重新溶解后可以在4℃冷藏保存至少2-7天;如果想延长保存时间,建议分装(加载体蛋白如0.1% HSA或 BSA)后置于-18℃冻存。请避免反复冻融。